Rapid test for antibiotic resistance could help control spread in hospitals

A new test, jointly developed between Imperial College and Bruker Daltonics, could help rapidly determine whether a bacterial infection is resistant to antibiotics of last resort.

The test kit can be used to test hospital patients on-site for bacterial infections that are resistant to colistin and other members of the antibiotic family known as polymyxins.

Polymyxins are used as a last resort antibiotic because they are often effective even against superbugs that are otherwise antibiotic-resistant.

The development could prove to be hugely significant given that the spread of bacterial resistance even to these last-line antibiotics is therefore a serious threat to human health.

Importantly, the test kit also helps indicate how transmissible a case of antibiotic resistance is.

Dr Gerald Larrouy-Maumus at the Department of Life Sciences and the MRC Centre for Molecular Bacteriology and Infection, the lead inventor of the technology, said: “By working with Bruker, which is a world leader in mass spectrometry for diagnostics, we have been able to go from the lab bench to the public, to address an important clinical need.”

“Antibiotic resistance, along with climate change and the COVID-19 pandemic, is a huge problem,” he added.

“If we do nothing by 2050, 10 million deaths a year will be attributed to antibiotic resistance, and we will see a huge economic loss of around 100 trillion dollars. So of course, we need to think about how we can address this global challenge. The test we have created is an important tool.”

Professor Anne Dell, head of Imperial’s Department of Life Sciences, added: “I’m very proud of the work that Gerald and colleagues have done with our partners at Bruker Daltonics to translate hard-won academic insights first into an invention, and now a commercially available technology, that promises to play an important role in addressing antibiotic resistance and ultimately in saving lives.”

Last month, researchers warned the world has “a huge task” to stem the overuse of antibiotics which are rising fears of the rise in resistant bacteria.

The study, by the Global Research on Antimicrobial Resistance (GRAM) Project, found global antibiotic consumption rates increased by 46 percent in the last two decades. It is the first study to provide longitudinal estimates for human antibiotic consumption covering 204 countries from 2000 to 2018.

Follow us on twitter: @risksEmerging

#KayBurley - Rachel Maclean told me that people just need to work more hours & then they wouldn't be poor

Liz Truss - That's a miss characterisation of what she said

KB - How is it a miss characterisation when she told me that twice?

Liz Truss - I didn't see the interview.. 🤦

A Paradigm Shift, From ‘Buying Insurance’ to ‘Selling Risk’ https://www.carriermanagement.com/features/2022/05/18/236260.htm?utm_source=dlvr.it&utm_medium=twitter

Keir Starmer describes working from home critic Jacob Rees-Mogg as “sticking notes on people’s desks like some overgrown prefect”.

Starmer asks Johnson whether he is in favour of a windfall tax or not

Johnson: "This government is not in principle in favour of higher taxation- they [Labour] love it, they love putting up taxes."

Worth noting that in April the government increased Nat Insurance- a tax.

Germany beer bottle shortage: Industry warns of 'tense' situation https://bbc.in/3MrkDBj

Meet The Athletic UK’s playing wheels, a new graphic to help show if a team is playing well or not.

Devised by @johnspacemuller, no numbers to get your head round, easy to understand.

All Premier League and Championship teams in this first piece.

Load More...